UHPLC Column, RP C12, 1.8um, 100A. 4.0mm ID x 100mm Length. Cogent Brand. 1 EA.

Additional Information:

Cogent RP C12™ is a unique reversed-phase UHPLC stationary phase featuring a rigid adamantane-like bonded phase on ultra-high purity silica. Fully double end capped and compatible with 100% aqueous mobile phases, it provides excellent retention stability, rapid re-equilibration, and highly reproducible performance. With hydrophobic retention typically greater than C8 phases and lower than C18 phases, RP C12™ is well suited for high-throughput screening, gradient methods, pharmaceutical analysis, and complex mixture separations.

68112-10P-4 is a UHPLC column packed with 1.8 µm RP C12™ particles with a 100 Å pore size in a 4.0 mm ID x 100 mm format. The 100 mm length provides enhanced resolution and peak capacity compared to shorter columns, while the sub-2 µm particle technology delivers outstanding chromatographic efficiency. Designed specifically for high-pressure UHPLC operation, this column provides optimal performance when used on UHPLC systems capable of handling the elevated pressures generated by 1.8 µm particles. Typical operating flow rates are approximately 0.8–1.5 mL/min depending on method conditions and instrument pressure capabilities.

This column is ideal for high-throughput screening, impurity profiling, pharmaceutical analysis, and complex mixture separations where rapid equilibration, aqueous mobile phase compatibility, and high chromatographic efficiency are required.

Key Benefits

  • RP C12™ stationary phase

  • Fully double end capped

  • Adamantane-like bonded phase chemistry

  • Compatible with 100% aqueous mobile phases

  • Rapid re-equilibration between runs

  • High-efficiency 1.8 µm particles

  • Excellent for complex mixtures

  • Increased peak capacity

  • Improved chromatographic resolution

  • Reduced solvent consumption

Typical Applications

  • UHPLC analysis

  • High-throughput screening (HTS)

  • Pharmaceutical analysis

  • Impurity profiling

  • Complex mixture separations

  • Gradient methods

  • Quality control testing

  • Stability studies

  • Environmental analysis

  • Research and development

Specifications

  • Product Type: UHPLC Column

  • Stationary Phase: RP C12™

  • Chromatography Mode: Reversed Phase

  • Bonded Phase: Adamantane-Like Carbon Silane

  • Endcapping: Fully Double End Capped

  • Particle Size: 1.8 µm

  • Pore Size: 100 Å

  • Column Dimensions: 4.0 mm ID x 100 mm

  • Length: 100 mm

  • Typical Flow Rate: 0.8–1.5 mL/min

  • Brand: Cogent

Special Order Item Information

Important Notes

  • Designed specifically for UHPLC operation and high-pressure reversed-phase chromatography

  • 1.8 µm particles generate substantially higher backpressure than conventional HPLC columns

  • Maximum performance is achieved on UHPLC systems designed for sub-2 µm particle technology

  • Compatible with 100% aqueous mobile phases without loss of retention

  • The 100 mm length provides greater resolution and peak capacity than 50 mm columns

  • Samples should be filtered through a 0.2 µm syringe filter prior to injection

  • May be used on compatible HPLC systems only if instrument pressure limits are not exceeded

  • This is a Special Order Item


 

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